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Adrenal Necrosis induced by 7-Hydroxymethyl-12-methylbenz(a)anthracene and its Prevention

Abstract

THIS communication reports our investigation of the action of 7-hydroxymethyl-12-methylbenz(a)anthracene (7-OHM-MBA) on the adrenal glands of normal rats and of rats treated by methods that protect the adrenal glands against 7,12-dimethylbenz(a)anthracene (9,10-dimethyl-1,2-benzanthracene, or DMBA)1,2.

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References

  1. Currie, A. R., Helfenstein, J. E., and Young, S., Lancet, ii, 1199 (1962).

  2. Wheatley, D. N., Kernohan, I. R., and Currie, A. R., Nature, 211, 387 (1966).

    Article  ADS  CAS  Google Scholar 

  3. Huggins, C., and Morii, S., J. Exp. Med., 114, 741 (1961).

    Article  CAS  Google Scholar 

  4. Wheatley, D. N., Gerrard, M. E., and Currie, A. R. (in preparation).

  5. Boyland, E., and Sims, P., Biochem. J., 95, 780 (1965).

    Article  CAS  Google Scholar 

  6. Boyland, E., Sims, P., and Huggins, C., Nature, 207, 816 (1965).

    Article  ADS  CAS  Google Scholar 

  7. Dao, T. L., and Tanaka, Y., Proc. Soc. Exp. Biol. N.Y., 113, 78 (1963).

    Article  CAS  Google Scholar 

  8. Chart, J. J., Sheppard, H., Allen, M. J., Bencze, W. L., and Gaunt, R., Experientia, 14, 151 (1958).

    Article  CAS  Google Scholar 

  9. Wong, T. W., and Warner, N. E., Endocrinology, 74, 284 (1964).

    Article  CAS  Google Scholar 

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WHEATLEY, D., CURRIE, A., HAMILTON, A. et al. Adrenal Necrosis induced by 7-Hydroxymethyl-12-methylbenz(a)anthracene and its Prevention. Nature 211, 1311–1312 (1966). https://doi.org/10.1038/2111311a0

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