Abstract
THE pattern of the metabolic response by man and the rat to injury (for example, fracture of a long bone) has been under investigation for some time. The reaction is characterized by a marked rise in the urinary excretions of nitrogen, sulphur, phosphorus, potassium and creatme, which reach a peak in the rat at the third day after the injury and then slowly decline1–3. It was early noted that in man once shock had subsided there was also a rise in the ‘basal’ consumption of oxygen and a slight rise in body temperature paralleling the increase in the catabolites1. It was suggested that following injury there is an increased demand for energy from endogenous sources2,4,5. At that time it seemed reasonable to assume that in some way by releasing energy from endogenous sources metabolism is raised following moderate to severe injury and this facilitates the healing process.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Cuthbertson, D. P., Quart. J. Med., 25 (1, New Series) 233 (1932).
Cuthbertson, D. P., McGirr, J. L., and Robertson, J. S. M., Quart. J. Exp. Physiol., 29, 13 (1939).
Campbell, R. M., Sharp, G., Boyne, A. W., and Cuthbertson, D. P., Brit. J. Exp. Path., 35, 566 (1954).
Cuthbertson, D. P., Brit. J. Surg., 23, 305 (1936).
Cuthbertson, D. P., Lancet, i, 433 (1942).
Cairnie, A. B., Campbell, R. M., Pullar, J. D., and Cuthbertson, D. P., Brit. J. Exp. Path., 38, 504 (1957).
Munro, H. K., and Cuthbertson, D. P., Biochem. J., 37, XII (1943).
Wilkinson, A. W., Lancet, ii, 428 (1956).
Caldwell, F. T., jun., Ann. Surg., 155, 119 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CAMPBELL, R., CUTHBERTSON, D. Effect of Environmental Temperature on the Metabolic Response to Injury. Nature 210, 206–208 (1966). https://doi.org/10.1038/210206b0
Issue Date:
DOI: https://doi.org/10.1038/210206b0
This article is cited by
-
Ambient temperature and postoperative catabolism
Intensive Care Medicine (1990)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
