Abstract
INDIVIDUAL, animals of a given species show well-defined, genetically controlled differences in the composition of certain isofunctional proteins. This molecular polymorphism is essentially of two types. The first type is one in which an isofunctional protein such as haemoglobin is present in all individuals of the species and the individuals differ from one another by the amino-acid sequence in limited regions of the molecule. The second type of polymorphism is characterized by the presence or absence of a particular protein in different animals of the same species. We wish to propose here a general nomenclature for these two polymorphic states.
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References
Oudin, J., C.R. Acad. Sci., Paris, 242, 2606 (1956).
Medawar, P., Nature, 207, 1327 (1965).
Cinader, B., Dubiski, S., and Wardlaw, A. C., J. Exp. Med., 120, 897 (1964).
Cinader, B., and Dubiski, S., Nature, 202, 102 (1964).
Cinader, B., Nature, 188, 619 (1960).
Cinader, B., and Dubiski, S., in La Tolérance acquise et la Tolérance Naturelle a l'Égard de Substances Antigéniques Définies, Royamount 25–28juin 1962 , edit. by Bussard, A., 255 (Centre National de la Recherche Scientifique, Paris, 1963).
Biggs, R., and Macfarlane, R. G., Human Blood Coagulation and its Disorders, third ed. (Blackwell Scientific Publications, Oxford, 1962).
Stefanini, M., and Dameshek, W., Hemorrhagic Disorders, second ed. (Grune and Stratton, New York, 1962).
Harris, H., Human Biochemical Genetics (Cambridge Univ. Press, London, 1959).
Hsia, D. Y., Inborn Errors of Metabolism (Year Book Publishers, Chicago. 1959).
Aebi, H., Heiniger, J. P., Bütler, R., and Hässig, A., Experientia, 17, 466 (1961).
Takahara, S., Lancet, ii, 1101 (1952).
Harris, H., in Second Intern. Conf. Congenital Malformations, New York City, July 14–19, 1963 , edit. by International Medical Congress, Ltd., 135 (International Medical Congress, Ltd., New York, 1964).
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CINADER, B., DUBISKI, S. & WARDLAW, A. Allotypy and Eniotypy. Nature 210, 1291–1292 (1966). https://doi.org/10.1038/2101291b0
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DOI: https://doi.org/10.1038/2101291b0
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