Abstract
MANY parts of the mammalian brain, isolated and examined in simple media in vitro, afford metabolic responses to electrical stimulation. It has not hitherto been established whether this implies neuronal responses detectable electrically. Thus in spite of much effort, no responses were recorded from the surface of slices of mammalian cerebral cortex1, though metabolic sequelae to stimulation were observed.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hillman, H. H., Campbell, W. L., and McIlwain, H., J. Neurochem., 10, 325 (1963).
Gibson, I. M., and McIlwain, H., J. Physiol., 176, 261 (1965).
Cajal, S. R. y., Studies on the Cerebral Cortex, trans. from Spanish by Kraft, L. M. (Lloyd-Luke, London, 1956).
Valverde, F., Studies of the Piriform Lobe (Harvard University Press, Cambridge, 1965).
Eccles, J. C., The Physiology of Synapses (Academic Press, New York, 1964).
Coombs, J. S., Eccles, J. C., and Fatt, P., J. Physiol., 130, 374 (1955).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
YAMAMOTO, C., MCILWAIN, H. Potentials evoked in vitro in Preparations from the Mammalian Brain. Nature 210, 1055–1056 (1966). https://doi.org/10.1038/2101055a0
Issue Date:
DOI: https://doi.org/10.1038/2101055a0
This article is cited by
-
Modified Recording Chamber for Sustained Kainate-Induced Gamma Oscillations in Submerged Rat Hippocampal Slices
BioNanoScience (2017)
-
Dendritic integration: 60 years of progress
Nature Neuroscience (2015)
-
Recording of electrical activity from microscopically identified neurons of the mammalian brain
Experientia (1975)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
