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Gm(b) Factor in the γ Globulin of Non-human Primates

Abstract

RECENT investigations in man have shown that the Gm factors of γG globulin are linked to non-segregating antigenic determinants which define at least four different classes of heavy polypeptide chains in human γG globulin1. Studies in man have also suggested that the Gm(b) factor is not unique, but rather is pleomorphic and may vary in different human races2. Certain of the Gm genetic factors including Gm(b) have been recognized in the serum of some non-human primates3,4. It therefore became of interest to assess the Gm(b) factor as it occurred in non-human primates, to evaluate any pleomorphism and to investigate its relationship to the H-chain subgroup with which the Gm(b) factor is known to be associated in man.

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References

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ALLEN, J. Gm(b) Factor in the γ Globulin of Non-human Primates. Nature 209, 520–521 (1966). https://doi.org/10.1038/209520a0

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