Abstract
THE role of red blood cell group antigens in human histocompatibility has long been a matter of controversy1–6. It has recently been noted by Griffiths and Crikelair7, and by Kuhns, Rapaport et al.8, that a rise in anti-A and anti-B antibodies may occur following the exchange of skin homografts between blood group-incompatible subjects. This communication describes a series of experiments which provide suggestive evidence that erythrocyte group antigens may, on suitable immunization of recipients, play a significant part in conditioning the response of these subjects to first-set skin homografts.
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DAUSSET, J., RAPAPORT, F. Role of ABO Erthrocyte Groups in Human Histocompatibility Reactions. Nature 209, 209–211 (1966). https://doi.org/10.1038/209209a0
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DOI: https://doi.org/10.1038/209209a0
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