Abstract
MOST of the present knowledge about the ability of mosquitoes to serve as natural hosts for arthropod-borne viruses is based on two methods. The first consists of triturating the wild-caught mosquito and inoculating it into a laboratory animal; subsequent virus isolation proves natural infection of the mosquito but not ability to transmit. The second consists of infecting the mosquito on a viraemic laboratory host and demonstrating transmission by bite to another laboratory host. This method demonstrated the ability to transmit, but may not reflect what happens under natural conditions. The technique described here makes possible a demonstration of transmission by naturally infected arthropods.
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TODA, A., SHOPE, R. Transmission of Guamá and Oriboca Viruses by Naturally Infected Mosquitoes. Nature 208, 304 (1965). https://doi.org/10.1038/208304a0
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DOI: https://doi.org/10.1038/208304a0
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