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A Modification System for Fingerprinting Haemoglobin

Abstract

THE technique of ‘fingerprinting’ developed by Ingram1 has proved to be of great value in the molecular analysis of haemoglobins. In principle, it is a combined paper electrophoresis and chromatography of the peptides released by enzymatic digestion, of haemoglobin. This enables the location of a probably occurring difference to a particular peptide. The method has proved its importance especially in the detection of amino-acid differences in normal and abnormal haemoglobins. This communication describes a modified system for fingerprinting haemoglobins.

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EFREMOV, G. A Modification System for Fingerprinting Haemoglobin. Nature 208, 298–299 (1965). https://doi.org/10.1038/208298a0

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  • DOI: https://doi.org/10.1038/208298a0

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