Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of Trans-Solutes on the Fluxes of Chloride Ions across Artificial Membranes

Nature volume 208, pages 187–189 (1965)Cite this article

Abstract

IN free diffusion across membranes the unidirectional fluxes of a solute are usually treated as mutually independent movements: each flux being a function only of the electrochemical potential of its solute in the compartment from which it originates (cis side). Across biological membranes, however, such as the gastric mucosa of the frog1, or some cellular membranes2–4, the fluxes of various solutes strongly depend on the nature of the solutes on the trans side. These trans effects have been interpreted in terms of a carrier exchange mechanism with different affinity to different ions and molecules5,2. In the present work such trans effects have been studied in artificial membranes, in which transport or exchange carriers can be excluded.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Heinz, E., and Durbin, R. P., J. Gen. Physiol., 41, 101 (1957).

    Article  CAS  Google Scholar 

  2. Heinz, E., J. Biol. Chem., 211, 781 (1954).

    CAS  PubMed  Google Scholar 

  3. Heinz, E., and Walsh, P. M., J. Biol. Chem., 233, 1488 (1958).

    CAS  PubMed  Google Scholar 

  4. Rosenberg, T., and Wilbrandt, W., J. Gen. Physiol., 41, 289 (1957).

    Article  CAS  Google Scholar 

  5. Durbin, R. P., Stahlmann, C., Kitahara, S., and Heinz, E., Amer. J. Physiol. (in the press).

  6. Kedem, O., in Membrane Transport and Metabolism, 87 (Czechoslovak Academy of Sciences, Prague, 1960).

    Google Scholar 

  7. Handbook of Chemistry and Physics (Chemical Rubber Publishing Co., Cleveland, Ohio, 1952).

  8. Durbin, R. P., J. Gen. Physiol., 44, 315 (1960).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute for Vegetative Physiology, University of Frankfurt a. Main,

    S. KITAHARA, E. HEINZ & C. STAHLMANN

Authors
  1. S. KITAHARA
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. HEINZ
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. STAHLMANN
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

KITAHARA, S., HEINZ, E. & STAHLMANN, C. Effect of Trans-Solutes on the Fluxes of Chloride Ions across Artificial Membranes. Nature 208, 187–189 (1965). https://doi.org/10.1038/208187a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/208187a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing