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Effects of Pyridoxine Deficiency on the Adaptation of Rat Liver Cystathionase to DL-Ethionine and to Thyroidectomy

Nature volume 207, pages 1390–1391 (1965)Cite this article

Abstract

THE activity of liver cystathionase (‘soluble’ cysteine desulphydrase) of rats is adaptively increased both after thyroidectomy1 and after feeding DL-ethionine2. Since pyridoxal phosphate (PLP) is the co-enzyme of cystathionase3, it was of interest to determine the effect of pyridoxine deficiency on the level of liver cystathionase. Experiments were also conducted to determine the adaptive increase of cystathionase in pyridoxine-deficient rats in response to thyroidectomy and to ethionine feeding.

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Authors and Affiliations

  1. Laboratoire de Chimie Biologique, 96 Boulevard Raspail, Paris

    FERNANDE CHATAGNER & ODILE DURIEU-TRAUTMANN

Authors
  1. FERNANDE CHATAGNER
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  2. ODILE DURIEU-TRAUTMANN
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CHATAGNER, F., DURIEU-TRAUTMANN, O. Effects of Pyridoxine Deficiency on the Adaptation of Rat Liver Cystathionase to DL-Ethionine and to Thyroidectomy. Nature 207, 1390–1391 (1965). https://doi.org/10.1038/2071390a0

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