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Electron-microscopic Demonstration of Bacteria in the Skin of Patients with Lichen Ruber Planus

Abstract

THE aetiology of lichen ruber planus is uncertain. A number of hypotheses have been advanced1. Lichen ruber planus eruptions have been observed in connexion with the use of different drugs, for instance atebrin. In these cases, however, it has not yet been determined whether it is a matter of a genuine lichen or of a lichenoid dermatosis. In cases in which a relation to drugs is out of the question two main possibilities have been put forward, namely, those of an infectious or a nervous aetiology. Conclusive proof for any of these theories has not yet been presented. As infectious agents, viruses and spirochaetes have been suggested. The therapeutic success attained in some cases with chemotherapeutics and antibiotics has been adduced as an argument in favour of an infectious aetiology1.

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BRODY, I. Electron-microscopic Demonstration of Bacteria in the Skin of Patients with Lichen Ruber Planus. Nature 207, 96–98 (1965). https://doi.org/10.1038/207096a0

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