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Separation of Factor VIII (Antihaemophilic Factor) Activity from Fibrinogen by Means of a Snake Venom

Nature volume 207, pages 90–91 (1965)Cite this article

Abstract

THE separation of Factor VIII activity from fibrinogen is of considerable importance. From the therapeutic point of view it would seem desirable when treating haemophiliacs to use a protein fraction rich in factor VIII activity but as free as possible from other contaminating proteins, including fibrinogen. From the experimental point of view purified Factor VIII is required for studies of its chemical and physical properties.

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Authors and Affiliations

  1. Department of Pharmacology and Therapeutics, Queen's College, Dundee

    C. R. RIZZA, K. E. CHAN & MARIE P. HENDERSON

  2. Clinical Investigation Unit, Maryfield Hospital, Dundee

    C. R. RIZZA, K. E. CHAN & MARIE P. HENDERSON

Authors
  1. C. R. RIZZA
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  2. K. E. CHAN
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  3. MARIE P. HENDERSON
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RIZZA, C., CHAN, K. & HENDERSON, M. Separation of Factor VIII (Antihaemophilic Factor) Activity from Fibrinogen by Means of a Snake Venom. Nature 207, 90–91 (1965). https://doi.org/10.1038/207090a0

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  • DOI: https://doi.org/10.1038/207090a0

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