Abstract
SYSTEMIC administration of corticotrophin, cortisone and hydrocortisone causes degranulation and other changes in mast cells1–3. Exposure of rats to cold caused the number of mast cells in lung and thymus tissue to increase in rats weighing 185 g and decrease in rats weighing 380 g (ref. 4). Cold treatment of the heavier rats increased the number of dermal mast cells and decreased mesentery (intervascular) mast cells5.
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CASTELLI, A., CLAY, M. Effect of Cold and Restriction of Movement on Mast Cells and Metachromasia of Rat Skin. Nature 207, 89–90 (1965). https://doi.org/10.1038/207089b0
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DOI: https://doi.org/10.1038/207089b0
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