Abstract
α-METHYL-m-tyrosine and α-methyl-DOPA deplete endogenous catecholamine stores of heart and brain. The drop in endogenous catecholamine-levels appears to be due to a displacement by metabolites of these amino-acids and particularly by their decarboxylation and β-hydroxylation products: metaraminol (‘Aramine’) and α-methyl-noradrenaline (‘Corbasil’), respectively1–6.
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MAÎTRE, L., STAEHELIN, M. Presence of α-Methyl-noradrenaline (‘Corbasil’) in the Heart of Guinea-pigs Treated with Metaraminol (‘Aramine’). Nature 206, 723–724 (1965). https://doi.org/10.1038/206723a0
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DOI: https://doi.org/10.1038/206723a0
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Orientierende Übersicht
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie (1966)
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