Abstract
THE effects of amino-chlorambucil, an alkylating agent, on the establishment of homografts of haemopoietic tissue in rabbits have been described by Cree1. The preliminary experiments described here illustrate the effectiveness of a related compound, chlorambucil, in suppressing certain immunological responses in the sheep.
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References
Cree, I. C., Lancet, i, 1104 (1962).
Soulsby, E. J. L., and Stewart, D. F., Austral. J. Agric. Res., 11, 595 (1960).
Elson, L. A., Brit. J. Hæmatol., 1, 104 (1955).
Bouroncle, B. A., Doan, C. A., Wiseman, B. K., and Frajola, W. J., Arch. Int. Med., 97, 703 (1956).
Soulsby, E. J. L., Ann. N.Y. Acad. Sci., 113, 492 (1963).
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SOULSBY, E., OWEN, L. Lowering of Immunity in Sheep following Injections of Chlorambucil. Nature 205, 719–720 (1965). https://doi.org/10.1038/205719a0
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DOI: https://doi.org/10.1038/205719a0
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