Abstract
A PROPORTION of the mammary tumours induced in rats by oral administration of 9,10-dimethyl-1,2-benz-anthracene (DMBA) have been found to undergo spontaneous regression1. Attempts to stimulate regressing tumours to grow again by hormonal means have been unsuccessful, and it appears possible that this regression may be due to an immunological mechanism2. If this is so it might be possible to demonstrate the presence of anti-tumour antibodies on tumour cells by using Coon's fluorescent antibody technique.
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Young, S., Cowan, D. M., and Sutherland, L. E., J. Path. Bact., 85, 331 (1963).
Young, S., and Cowan, D. M., Brit. J. Cancer, 17, 85 (1963).
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YOUNG, S., COWAN, D. ‘Immuno-fluorescence’ of Mast Cells. Nature 205, 713 (1965). https://doi.org/10.1038/205713a0
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DOI: https://doi.org/10.1038/205713a0
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