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A Comparison of 3H- and 14C-Glucose Metabolism in the Intact Rat

Abstract

DURING the course of using glucose-6-3H in an investigation of glucose turnover in rats, apparent values were obtained for the size of the body glucose pool, the glucose space, and the rates of glucose production and utilization, which were obviously too large when compared to similar work1,2 using glucose labelled with carbon-14. The possibility was considered that the tritium label on carbon six did not represent the entire glucose molecule, thereby giving inaccurate values for the foregoing parameters of carbohydrate metabolism.

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DUNN, A., STRAHS, S. A Comparison of 3H- and 14C-Glucose Metabolism in the Intact Rat. Nature 205, 705–706 (1965). https://doi.org/10.1038/205705a0

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