Abstract
THE importance of nucleoproteins in antibody-globulin production is well known1,2. In previous experiments3,4 an evident increase of the content of RNA in the γ-globulin fraction in immune sera has been observed. The RNA extracted from the serum of immunized rabbits is capable of eliciting in normal rabbits the production of antibodies against the same antigens used for immunizing the animals from which this RNA-immuno-carrier (RNA-I-C) was taken. The following investigations were undertaken to ascertain whether an RNA-I-C extracted from the serum of immunized animals of one species was able to induce antibody production in animals of a different species.
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MICHELAZZI, L., BALDINI, I., NOVELLI, A. et al. Immune Response induced by RNA-Immuno-carrier extracted from Heterologous Immune Sera. Nature 205, 194 (1965). https://doi.org/10.1038/205194a0
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DOI: https://doi.org/10.1038/205194a0
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