Abstract
WE have shown1 that primycin, an agent of strong antituberculotic effect belonging to the group of guanidino antibiotics, is not identical with any of the known antibiotics. On the basis of its colour reactions and of its infra-red and ultra-violet spectra2, the molecule of primycin (C19H37O7N)n contains an N—H group and several O—H groups; it is inclined to molecular associations and it discloses adsorptive properties. On subjecting primycin to paper chromatography, the formation of a second spot was observed. This was due to the so-called ‘secondary adsorption’ of an accompanying substance present in minute amounts.
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References
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Uri, J. (personal communication).
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SZILÁGYI, I., VÁLYI-NAGY, T. & KERESZTES, T. Formation of Two Spots caused by ‘Secondary Adsorption’ in Paper Chromatography of Primycin. Nature 205, 1225–1227 (1965). https://doi.org/10.1038/2051225b0
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DOI: https://doi.org/10.1038/2051225b0
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