Abstract
Pappenheimer and Goettsch1 described the symptoms of chick encephalomalacia produced by vitamin E deficiency and indicated that capillary thrombosis may be the primary cause of the observed ischaemic necrosis. Muscular dystrophy of vitamin E-deficient rabbits may be considered the counterpart of experimental encephalomalacia in chicks since both diseases can be produced by lack of dietary vitamin E.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Pappenheimer, A. M., and Goettsch, M., J. Exp. Med., 53, 11 (1931).
Weinstock, I. M., Goldrich, A. D., and Milhorat, A. T., Proc. Soc. Exp. Biol. and Med., 88, 257 (1955).
Kozalka, T. R., Mason, K. E., and Krol, G., J. Nutrition, 73, 78 (1961).
Zalkin, H., Tappel, A. L., Caldwell, K. A., Shibko, S., Desai, I. D., and Holliday, T. A., J. Biol. Chem., 237, 2678 (1962).
Jibril, A. O., Ph.D. dissertation, University of Oklahoma (1964).
De Duve, C., Pressman, B. C., Gianetto, R., Wattiaux, R., and Applemans, F., Biochem. J., 60, 604 (1955).
Koenig, H., Nature, 195, 782 (1962).
Carubelli, R., Trucco, R., and Caputto, R., Biochim. Biophys. Acta, 60, 196 (1962).
Morgan, E. H., and Laurel, C. B., Nature, 197, 921 (1963).
Caputto, R., McCay, P. B., and Carpenter, M. P., J. Biol. Chem., 233, 1025 (1958).
Fishman, W. H., Springer, B., and Bruntti, R., J. Biol. Chem., 173, 449 (1948).
Svennerholm, L., J. Lipid Res., 5, 145 (1964).
De Duve, C., and Beaufay, H., Biochem. J., 73, 610 (1959).
Van Lanker, J. L., and Holtzer, R. L., Amer. J. Path., 35, 563 (1959).
Doyle, W. L., J. Biophys. Biochem. Cytol., 1, 221 (1955).
Cohn, Z. A., and Hirsch, J. G., J. Exp. Med., 112, 983 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
JIBRIL, A., McCAY, P. Lysosomal Enzymes in Experimental Encephalomalacia. Nature 205, 1214–1215 (1965). https://doi.org/10.1038/2051214a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/2051214a0
This article is cited by
-
Beta-Glucuronidase activity, and levels of protein and protein fractions in serum and cerebrospinal fluid of dogs with distemper associated demyelinating encephalopathy
Acta Neuropathologica (1973)
-
Substrate specificity of neuraminidases
The Histochemical Journal (1973)
-
Mechanism of Action of β-N-Oxalyl-L-α,β-diaminopropionic Acid, Lathyrus sativus Neurotoxin: Effect on Brain Lysosomes
Nature New Biology (1971)
-
Enzymhistochemische und submikroskopische Untersuchungen zur Reparation der Rattenzirbeldr�se nach experimenteller Parenchymnekrose
Acta Neuropathologica (1968)
-
Lysosomes and essential fatty acid deficiency
Lipids (1967)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
