Abstract
Gillies and Alper1 and Suzuki2 described the high restorative effect of chloramphenicol (CAM) treatment, applied with some delay after ultra-violet irradiation, to E. coli B and B (H) respectively. CAM is known to inhibit protein synthesis and to affect the metabolism of RNA. Gillies3 also showed that inhibition of protein synthesis by omission of essential amino-acids from the medium immediately after irradiation affected a significant recovery of some deficient strains of E. coli.
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References
Gillies, N. E., and Alper, T., Nature, 183, 237 (1959).
Suzuki, K., and Iwama, Y., Nature, 187, 347 (1960).
Gillies, N. E., Intern. J. Rad. Biol., 3, 379 (1961).
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Kos, E., DRAKULIĆ, M. & BRDAR, B. Responses of Various Strains of Escherichia coli to Inhibition of some Biosynthetic Processes after Ultra-violet Irradiation. Nature 205, 1125–1126 (1965). https://doi.org/10.1038/2051125a0
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DOI: https://doi.org/10.1038/2051125a0
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