Abstract
OBSERVATIONS on living organs excited by ultra-violet irradiations have been almost entirely confined to work on experimental animals. The specific fluorescence method was largely developed through the work of Ellinger and Hirt1,2, who termed it intravital fluorescence microscopy. The method found use in the investigation of resorptive and excretory functions of different organs, and offered valuable information about the physico-chemical conditions and processes in living cells, in particular the electrostatic phenomena. It also helped in the elucidation of various problems concerning the function of kidneys3,4, liver5,6, blood vessels7, and nerves8, and other organs of experimental animals.
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SHERIF, M. Intravital Fluorescence Microscopy in the Qualitative Evaluation of the Interaction of Acridine Orange with Nucleic Acid in Intact Living Human Organs. Nature 204, 390–391 (1964). https://doi.org/10.1038/204390a0
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DOI: https://doi.org/10.1038/204390a0
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