Abstract
THE fraction of ox liver which contains those components soluble both in water and in acetone was found by Maisin and Lambert to have a powerful prophylactic effect against the liver carcinogen 4-dimethylaminoazobenzene (DMAB) when both were given in the diet1. It has been found in these laboratories that a diet supplemented with copper acetate affords a good degree of protection against this carcinogen2 and it was decided to test the ox liver fraction under our conditions so that the efficacy of the copper salt could be compared with that of the fraction.
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References
Maisin, J., and Lambert, G., Biological Approaches to Cancer Chemotherapy, 399 (Academic Press Inc., London, 1960).
Howell, J. S., Brit. J. Cancer, 12, 594 (1958).
Maisin, J. (private communication).
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FARE, G. Partial Protection by an Ox Liver Extract against Rat Liver Carcinogenesis by 4-Dimethylaminoazobenzene. Nature 204, 1004–1005 (1964). https://doi.org/10.1038/2041004a0
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DOI: https://doi.org/10.1038/2041004a0
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