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Multiplication of Rauscher Virus in Cultures of Mouse Kidney Cells

Abstract

RAUSCHER virus induces a characteristic malignant hæmopathy when inoculated into adult or new-born mice of various strains, mainly that of BALB/c (ref. 1). In order to handle a system which would give a good production of virus in vitro, we cultured cells taken from various organs of animals inoculated with Kauscher virus several days previously. Among the organs tested, we obtained valuable results with cultures of young mice kidneys. The kidney always being spared during the course of Rauscher leukæmia, this production of virus is worth while mentioning.

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References

  1. Rauscher, F. J., J. Nat. Cancer Inst., 29, 515 (1962).

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  2. Moloney, J., Fed. Proc., 21, 19 (1962).

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  3. Lasneret, J., Levy, J. P., and Boiron, M. (to be published).

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PERIES, J., LEVY, J., BOIRON, M. et al. Multiplication of Rauscher Virus in Cultures of Mouse Kidney Cells. Nature 203, 672–673 (1964). https://doi.org/10.1038/203672a0

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