Abstract
PAST investigations in many laboratories concerning the antigenicity of experimental tumours have revealed that almost all the sarcomas induced by carcinogenic hydrocarbons contain specific antigens. For this reason a certain pretreatment of isologous recipients with these tumours can produce resistance against cell inocula of the tumour originally taken for immunization. Using this test system specific antigens were demonstrated in sarcomas which were induced by administration of methylcholanthrene1–7, benzpyrene5,8,9, dibenzpyrene6, dibenzanthracene10, and dimethylbenzanthracene11.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Foley, E. J., Cancer Res., 13, 835 (1953).
Prehn, R. T., and Main, J. M., J. Nat. Cancer Inst., 18, 769 (1957).
Révész, L., Cancer Res., 20, 443 (1960).
Klein, G., Sjögren, H. O., Klein, E., and Hellström, K. E., Cancer Res., 20, 1561 (1960).
Koldovský, P., Folia biol., 7, 115 (1961).
Old, L. J., Benacerraf, B., Clarke, D. A., Carswell, E. A., and Stockert, E., Cancer Res., 21, 1281 (1961).
Pasternak, G., Graffi, A., and Horn, K.-H., Acta biol. med. germ., 9, 302 (1962).
Graffi, A., Pasternak, G., and Horn, K.-H., Acta biol. med. germ., 9, 318 (1962).
Feldman, M., Globerson, A., and Yaffe, D., Acta Unio Contra Cancr., 19, 65 (1963).
Prehn, R. T., Cancer Res., 20, 1614 (1960).
Pasternak, G., Acta biol. med. germ., 10, 572 (1963).
Prehn, R. T., Ann. N.Y. Acad. Sci., 101, 107 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PASTERNAK, G., GRAFFI, A., HOFFMANN, F. et al. Resistance against Carcinomas of the Skin induced by Dimethylbenzanthracene (DMBA) in Mice of the Strain XVII/Bln. Nature 203, 307–308 (1964). https://doi.org/10.1038/203307b0
Issue Date:
DOI: https://doi.org/10.1038/203307b0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.