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Influence of Cobalt on Propionibacterium freudenreichii

Abstract

IN recent years some attention has been devoted to study of Propionibacterium chiefly because of its ability to synthesize appreciable amounts of vitamin B12. Several authors1–6, working with different species of Propionibacterium, reported high vitamin B12 activity under different culture conditions3–6. However, there is lack of sufficient experimental evidence to ascertain optimum conditions for its growth and synthesis of vitamin B12. In this connexion, we have carried out experiments on the influence of cobalt on the growth characteristics of P. freudenreichii. This work was undertaken as a consequence of our recent report7 that cobalt stimulated vitamin B12 content of activated sludge.

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References

  1. Leviton, A., and Hargrove, R. S., Indus. Eng. Chem., 44, 2651 (1952).

    Article  CAS  Google Scholar 

  2. Riley, P. B., Jackson, P. W., Ross, D., and Savage, P. A., Continuous Culture of Microorganisms, S.C.I. Monograph No. 12, 127 (1961).

    Google Scholar 

  3. Janicki, J., and Pawelkeiwiez, J., Acta Biochem. Polon., 1, 307 (1954).

    CAS  Google Scholar 

  4. Pawelkeiwiez, J., Acta Biochem. Polon., 1, 313 (1954).

    Google Scholar 

  5. Perlman, D., and Barrett, J. M., Canad. J. Microbiol., 4, 9 (1958).

    Article  CAS  Google Scholar 

  6. Neujahr, H. Y., Kurz, W. G., and Ross-Ricci, G., Arkiv. Kemi., 15, 363 (1960).

    CAS  Google Scholar 

  7. Sathyanarayana Rao, S., and Srinath, E. G., J. Sci. Indust. Res., 20c, 261 (1961).

    Google Scholar 

  8. Skeggs, H. R., Nipple, H. M., Valentik, K. A., Huff, J. W., and Wright, L. D., J. Biol. Chem., 184, 211 (1950).

    CAS  PubMed  Google Scholar 

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RAO, S., WASHINGTON, D. Influence of Cobalt on Propionibacterium freudenreichii. Nature 202, 212–213 (1964). https://doi.org/10.1038/202212a0

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