Abstract
WE have previously demonstrated that plasma clots and whole blood clots are very resistant to the action of trypsin and α-chymotrypsin in saline but can be lysed by solutions of trypsin and α-chymotrypsin in 50 per cent glycerol in saline. A fibrin clot, however, prepared from bovine fibrinogen is not resistant to trypsin or α-chymotrypsin in saline although it can be lysed more quickly by trypsin or α-chymotrypsin in 50 per cent glycerol in saline1.
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References
Dunstone, G. H., Fleming, L. B., Porter, I. A., and Walder, D. N., Brit. J. Surg., 51, 227 (1964).
Lorand, L., Thromb. Diath. Haem., 7, 238 (1962).
Hartert, H., Flow Properties of Blood and Other Biological Systems, edit. by Copley, A. L., and Stainsby, G., 194 (Pergamon Press, London, 1960).
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ABEYARATNE, M., PORTER, I. & WALDER, D. Effect of Glycerol on the Resistance of Blood and Plasma Clots to the Action of Proteolytic Enzymes. Nature 202, 98–99 (1964). https://doi.org/10.1038/202098a0
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DOI: https://doi.org/10.1038/202098a0
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