Abstract
SEVERAL blood group antigens are more strongly reactive on adult red cells than on the red cells of new-born infants. A notable exception is the antigen i, which is maximally developed at birth and decreases in strength during the first year of life1. The decrease in antigen i is associated with a reciprocal increase in antigen I, which is poorly developed at birth.
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References
Marsh, W. L., Brit. J. Hœmat., 7, 200 (1961).
Tippett, P., Noades, J., Sanger, R., Race, R. R., Sausais, L., Holman, C. A., and Buttimer, R. J., Vox Sang., 5, 107 (1960).
Baglioni, C., in Molecular Genetics, edit. by Taylor, J. H., 405 (Academic Press, New York, 1963).
Dacie, J. V., Lewis, S. M., and Tills, D., Brit. J. Hœmat., 6, 362 (1960).
Lewis, S. M., Dacie, J. V., and Tills, D., Brit. J. Hæmat., 7, 64 (1961).
Lewis, S. M., Brit. J. Hæmat., 8, 322 (1962).
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GIBLETT, E., CROOKSTON, M. Agglutinability of Red Cells by Anti-i in Patients with Thalassæmia Major and Other Hæmatological Disorders. Nature 201, 1138–1139 (1964). https://doi.org/10.1038/2011138a0
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DOI: https://doi.org/10.1038/2011138a0
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