Abstract
SINCE the advent of starch-gel electrophoresis various enzymes, including serum cholinesterase1, erythrocyte glucose-6-phosphate dehydrogenase2 and erythrocyte acid phosphatase3, have been demonstrated to exist in human beings in different genetically determined modifications. We report here a procedure for the detection of human red-cell 6-phosphogluconate dehydrogenase (6-PGD) by starch-gel electrophoresis, and the existence of this enzyme in different genetically determined forms.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Harris, H., Hopkinson, D. A., and Robson, E. B., Nature, 196, 1296 (1962).
Boyer, S. H., Porter, I. H., and Weilbacher, G., Proc. U.S. Nat. Acad. Sci., 48, 1868 (1962). Kirkman, H. N., Amer. J. Dis. Child., 104, 566 (1962).
Hopkinson, D. A., Spencer, N., and Harris, H., Nature, 199, 969 (1963).
Smithies, O., Adv. Protein Chem., 14, 65 (1959).
Fildes, R. A., and Parr, C. W., Biochem. J., 87, 45P (1963).
Glock, G. E., and McLean, P., Biochem. J., 55, 400 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FILDES, R., PARR, C. Human Red-cell Phosphogluconate Dehydrogenases. Nature 200, 890–891 (1963). https://doi.org/10.1038/200890a0
Issue Date:
DOI: https://doi.org/10.1038/200890a0
This article is cited by
-
Study of enzyme polymorphism and haemoglobin patterns amongst sixteen tribal populations of central India (Orissa, Madhya Pradesh, and Maharashtra)
Japanese Journal of Human Genetics (1993)
-
Biochemical polymorphisms and phenetic relationships in rodents of the genusCtenomys from Southern Brazil
Biochemical Genetics (1991)
-
Biochemical polymorphisms and phenetic relationships in rodents of the genusCtenomys from Southern Brazil
Biochemical Genetics (1991)
-
Genetic variability in natural populations of the Brazilian night monkey (Aotus infulatus)
International Journal of Primatology (1989)
-
A report of four different unusual 6-PGD electrotypes in Caucasian and Negro populations
Human Genetics (1988)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.