Abstract
POLYMORPHISM, detected by antibody from individuals of the same species (allotypy), has so far been observed only in the γ- (ref. 1) and β-globulins (ref. 2). In man, a class of α-globulin Gc1 and Gc2 is subject to genetic variations and has been revealed by antibodies of heterologous origin3. Polymorphism of other α-globulins, the haptoglobins in several mammalian1 species and recently the trypsin inhibitors in man4,5 have been detected by other means. So far, the polymorphism of serum proteins has been most thoroughly examined in man and rabbit. In the mouse the genetic variation of the transferrins6 and of an allelic pair of γ-globulins (MuA1 and MuA2) (refs. 7–10) have been examined. We wish to report here a new allotypic specificity among the γ-globulins of the mouse.
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CINADER, B., DUBISKI, S. An Alpha-globulin Allotype in the Mouse (MuB1). Nature 200, 781 (1963). https://doi.org/10.1038/200781a0
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DOI: https://doi.org/10.1038/200781a0
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