Abstract
CHROMOSOMAL and non-chromosomal mutations to streptomycin resistance have been described in Chlamydomonas reinhardi1–3. The chromosomal mutants, sr-1, are resistant to low levels of streptomycin (50–100 µg/ml.), possess a Mendelian pattern of inheritance, are closely linked or allelic, and lie in the left arm of linkage group IX. The non-chromosomal mutants, sr-2, are resistant to high levels of streptomycin (500 µg/ml.) and exhibit a uniparental pattern of inheritance. When a mating is made between wild-type cells (ss) and cells of an sr-2 mutant, all the progeny in each tetrad are, with rare exceptions1,4, endowed with the resistance-level of the mating type plus (mt+) parent. The purpose of the present communication is to show that this pattern breaks down when diploids are made between sr-2 and ss cells and that a large proportion of the diploid clones segregate both resistant and sensitive cells during vegetative growth.
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GILLHAM, N. Transmission and Segregation of a Non-chromosomal Factor controlling Streptomycin Resistance in Diploid Chlamydomonas. Nature 200, 294 (1963). https://doi.org/10.1038/200294a0
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DOI: https://doi.org/10.1038/200294a0
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