Abstract
THE effect of whole body irradiation on rodents with lethal doses of X-rays or γ-rays is one of the most widely investigated phenomena. Mortality depends on the total dose, intensity at which the dose is delivered, strain, sex and age of the animal. Both serial histological examination and direct counts demonstrate the rapid loss of nucleated cells from the bone marrow. The animals' failure to replenish the granulocytes, platelets and erythrocytes from the circulating blood is primarily responsible for the death, as a consequence of septicæmia, hæmorrhage and anæmia.
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References
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Barnothy, J. M., Nature, 200, 86 (1963).
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BARNOTHY, M. Reduction of Radiation Mortality through Magnetic Pre-treatment. Nature 200, 279–280 (1963). https://doi.org/10.1038/200279a0
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DOI: https://doi.org/10.1038/200279a0
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