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Orthogonal Diameters in the Analysis of Muscle Fibre Size and Form

Abstract

DISTRIBUTIONAL changes in sizes of fibres have been correlated with pathological processes affecting muscle. Micrometry of muscle fibres in histological cross-section, for example, has been frequently used to follow the course of denervation atrophy1. Unfortunately, the complex polygonal form of the fibre and the lack of a standard technique of measurement make it difficult to compare the results of different studies2.

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References

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SONG, S., SHIMADA, N. & ANDERSON, P. Orthogonal Diameters in the Analysis of Muscle Fibre Size and Form. Nature 200, 1220–1221 (1963). https://doi.org/10.1038/2001220a0

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