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Alkaline Phosphatases in Brain and Spinal Cord

Nature volume 200, pages 1216–1217 (1963)Cite this article

Abstract

THERE has been much controversy as to whether alkaline phosphatase is a single enzyme or whether a number of such enzymes are present in tissues. The evidence derived from inhibition and pH studies suggests the existence of a plurality of alkaline phosphatases1–3. The subject has been studied histochemically by Glick and Fischer4, Dempsey5, Friedenwald and Maengwyn-Davies6 and Bourne7. The results of these authors also suggest a multiplicity of alkaline phosphatases. Sandier and Bourne8 separated out a number of substrate specific phosphatases by starch-gel electrophoresis, thus again indicating the plurality of alkaline phosphatase.

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Authors and Affiliations

  1. Department of Anatomy, and Yerkes Regional Primate Research Center of Emory University, Atlanta, 22, Ga.

    K. NANDY & G. H. BOURNE

Authors
  1. K. NANDY
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  2. G. H. BOURNE
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NANDY, K., BOURNE, G. Alkaline Phosphatases in Brain and Spinal Cord. Nature 200, 1216–1217 (1963). https://doi.org/10.1038/2001216a0

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