Abstract
PROTEIN solutions, generally used as maxima suppressors in polarographic work, are known to cause abnormal decrease in the diffusion current of metal ions due to factors such as adsorption1,2, viscosity3 and metal protein interaction4–6. The effect of increasing concentration of serum albumin on the limiting current of cadmium ion has been systematically investigated by Tanford4, who explained the marked decrease in the current in view of cadmium-protein complex formation. Investigations in this direction have not, so far, been undertaken in the case of gelatin, although the latter has been most widely used as the maximum suppressor. To meet this end, transfusion gelatin, a modified product of bone gelatin, with its well-characterized nature (in terms of hydrogen ion equilibria7 and mol. wt.8) was chosen and the effect of factors like pH, metal and protein concentration on the limiting current of cadmium was investigated.
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MALIK, W., SALAHUDDIN Polarography of Cadmium Transfusion–Gelatin Mixtures. Nature 200, 1204 (1963). https://doi.org/10.1038/2001204a0
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DOI: https://doi.org/10.1038/2001204a0
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