Abstract
RALL et al.1 have reported that, in animals bearing transplantable tumours, a yellow fluorescence was noted in the bones and the tumour tissue under ultra-violet light after treatment with any of the tetracyclines. Recently, McLeay2 and Klinger et al.3 presented the practical application of the tetracycline fluorescence for the detection of malignant tumour.
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References
Rall, D. P., Loo, T. L., Lane, M., and Kelley, M. G., J. Nat. Cancer Inst., 19, 79 (1957).
McLeay, J. F., Amer. J. Surg., 96, 415 (1957).
Klinger, J., and Katz, R., Gastroenterol., 41, 29 (1961).
Okamoto, K., Ueda, M., and Maeda, R., Microscopic Histochemistry, second ed., 128 (1958).
Sandell, E. B., Colorimetric Determination of Traces of Metals, second ed., 441 (1950).
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KATSUYA, H., KINOSHITA, T., DOI, Y. et al. Mercurochrome Fluorescence in Tumour Tissue. Nature 198, 497–498 (1963). https://doi.org/10.1038/198497a0
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DOI: https://doi.org/10.1038/198497a0
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