Abstract
THE pressure responses to intravenous injections of noradrenaline and adrenaline have often been shown to decrease during respiratory acidosis1,2. This decrease was more pronounced during acidosis in dogs with a total cardiac by-pass3 indicating that a decreased reactivity of peripheral blood vessels was one major cause. In accordance with these observations, it has been found that the vascular regions, perfused through the common carotid artery of dogs4 and via the femoral artery of cats5, responded less to noradrenaline during respiratory acidosis. In the work recorded here both skinned (group A) and unskinned (group B) leg preparations were perfused through the femoral artery and the reactivity changes during acidosis in the two groups were compared.
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BYGDEMAN, S. Reactivity of Skin and Muscular Blood Vessels to Noradrenaline during Induced Respiratory Acidosis in Cats. Nature 198, 491–492 (1963). https://doi.org/10.1038/198491a0
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DOI: https://doi.org/10.1038/198491a0
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