Abstract
ŒSTROGENS stimulate the activity of many enzymes present in the uterus of the ovariectomized mouse1. Histochemistry reveals the side of enzyme activity; but little is known about changes due to administration of progesterone. A histochemical investigation concerning the activity of a number of enzymes during pseudo-pregnancy and after progesterone administration to castrated mice has shown that in these circumstances marked changes occur. Increased activity of 5-nucleo-tidase in the endometrial stroma and in the myometrium was the most striking change. We used the technique of Wachstein and Meisel2.
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References
Leathem, J. H., Ann. N.Y. Acad. Sci., 75, 463 (1959).
Wachstein, M., and Meisel, E., Amer. J. Path., 27, 13 (1957).
Madjerek, Z., First Intern. Cong. Endocrinol., 8, h, No. 453 (1960).
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LAMMES, F., WILLIGHAGEN, R. Influence of Pseudopregnancy and Progesterone on the Activity of 5-Nucleotidase in the Uterus of Mice. Nature 198, 394–395 (1963). https://doi.org/10.1038/198394a0
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DOI: https://doi.org/10.1038/198394a0
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