Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Multiplication, Interferon Production and Sensitivity of Virulent and Attenuated Strains of the Virus of Foot-and-mouth Disease

Abstract

THE production of an interferon by the virus of foot-and-mouth disease was demonstrated by Dinter and Philipson1. Recently the existence of a relationship between lack of virulence of a virus and its ability to produce and be sensitive to interferon was shown by several workers2–6. Evidence has now been obtained that the same relationship may hold for certain strains of the virus of foot-and-mouth disease.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Dinter, Z., and Philipson, L., Proc. Soc. Exp. Biol. Med., 109, 893 (1962).

    Article  CAS  Google Scholar 

  2. Enders, J. F., Trans. Coll. Physicians Phila., 28, 68 (1960).

    PubMed  CAS  Google Scholar 

  3. De Maeyer, E., and Enders, J. F., Proc. Soc. Exp. Biol. Med. (in the press; quoted by ref.6).

  4. Wagner, R. R., Proc. Cold Spring Harbor Symp. Quant. Biol. (in the press; quoted by ref. 6).

  5. Ruis-Gomez, J., and Isaacs, A., Virology, 19, 1 (1963).

    Article  Google Scholar 

  6. Ruis-Gomez, J., and Isaacs, A., Virology, 19, 8 (1963).

    Article  Google Scholar 

  7. Palacios, C. A., Fuentes, R. A., Castañeda, J., and Maldonado, A., Bol. Inst. Inv. Vet., Maracay, 12, 3 (1960).

    Google Scholar 

  8. Zahran, G. E. D., Amer. J. Vet. Res., 22, 527 (1961).

    PubMed  CAS  Google Scholar 

  9. Frenkel, H. S., Bull. Off. int. Epiz., 28, 155 (1947).

    Google Scholar 

  10. Macpherson, I. A., and Stoker, M. G. P., Virology, 16, 147 (1962).

    Article  CAS  Google Scholar 

  11. Mowat, G. N., and Chapman, W. G., Nature, 194, 253 (1962).

    Article  ADS  CAS  Google Scholar 

  12. Sellers, R. F., and Fitzpatrick, M., Brit. J. Exp. Pathol., 43, 674 (1962).

    CAS  Google Scholar 

  13. Brooksby, J. B., Thorp, A. C. P., Davie, J., Mowat, G. N., and O'Reilly, K. J., Res. Vet. Sci., 3, 315 (1962).

    Article  Google Scholar 

  14. Mowat, G. N., and Prydie, J., Res. Vet. Sci., 3, 368 (1962).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

SELLERS, R. Multiplication, Interferon Production and Sensitivity of Virulent and Attenuated Strains of the Virus of Foot-and-mouth Disease. Nature 198, 1228–1229 (1963). https://doi.org/10.1038/1981228a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1981228a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing