Abstract
PREVIOUS experiments have shown that the uterus of the rabbit is resistant to experimental infection with Escherichia coli, when under the influence of œstrogens, but is susceptible to infection when under the influence of progesterone. Polymorphonuclear leucocytes are the agents mainly responsible for this bactericidal activity within the uterus, and the difference in bactericidal activity under the different hormonal conditions has been shown to correspond, in the early stages of infection, to different rates of leucocyte infiltration into the uterine lumen1–4.
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References
Broome, A. W. J., Lamming, G. E., and Smith, Wendy, J. Endocrinol., 19, 274 (1959).
Broome, A. W. J., Winter, A. J., McNutt, S. H., and Casida, L. E., Amer. J. Vet. Res., 21, 675 (1960).
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Killingbeck, J. (unpublished results).
Heap, R. B., and Lamming, G. E., J. Endocrinol., 20, 23 (1960).
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KILLINGBECK, J., LAMMING, G. Influence of Uterine Secretions on Phagoctyosis. Nature 198, 111–112 (1963). https://doi.org/10.1038/198111a0
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DOI: https://doi.org/10.1038/198111a0
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