Abstract
THE use of a hæmagglutination inhibition reaction for the diagnosis of pregnancy in women was reported by Wide and Gemzell1 and Wide2. In this reaction human chorionic gonadotrophin (HCG) inhibited the agglutination of stable HCG-coated blood cells. The same immunological technique was applied for the assay of pregnant mare serum gonadotrophin (PMS) and was used as a pregnancy diagnosis test in mares. Sera from pregnant mares containing elevated levels of gonadotrophin inhibited an agglutination reaction of PMS-coated formalinized erythrocytes in the presence of PMS anti-serum, while sera from non-pregnant mares did not give this reaction.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Wide, L., and Gemzell, C. A., Acta Endocrinol., 35, 261 (1960).
Wide, L., Acta Endocrinol., Suppl. 70 (1962).
Aschheim, S., and Zondek, B., Klin. Wschr., 6, 1322 (1927).
Cole, H. H., and Hart, G. H., Amer. J. Physiol., 93, 57 (1930).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WIDE, M., WIDE, L. Diagnosis of Pregnancy in Mares by an Immunological Method. Nature 198, 1017–1018 (1963). https://doi.org/10.1038/1981017a0
Issue Date:
DOI: https://doi.org/10.1038/1981017a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
