Abstract
IT is well established that only a small amount of the glucose consumed by the eye lens supplies carbon dioxide. The part played by the Krebs cycle in this oxidization and even the presence of the enzyme of this cycle have given rise to much controversy. According to Kinsey1 oxidative degradation occurs almost exclusively in the epithelium. However, the report of succinic dehydrogenase activity in eye lens homogenates2 and the inhibition of energy production in the fibres by potassium cyanide3 suggests the possible presence of an oxidative process outside the epithelium.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kinsey, V. E., and Frohyman, C. E., Arch. Ophthal., 46, 536 (1951).
Klethi, J., and Mandel, P., C.R. Soc. Biol., 148, 577 (1954).
Kleifeld, O., Muller, H. K., Hockwin, D., Arens, P., Fuchs, R., and Dardenne, U., Graefes Archiv Ophthal., 156, 443 (1955).
Virmaux, N., Porte, A., and Brini, A., Bull. Soc. Ophtal. France, 9–10, 1 (1961).
Hogeboom, G. H., Schneider, W. C., and Pallade, G. E., J. Biol. Chem., 172, 619 (1948).
Aldridge, W. N., and Johnson, M. K., Biochem. J., 73, 270 (1959).
Aldridge, W. N., and Parker, V. H., Biochem. J., 76, 47 (1960).
Vincendon, G., thesis, Strasbourg (1962).
Potter, V. E., in Manometric Techniques, third ed., 173 (1957).
Hunter, F. E., jun., in Methods in Enzymology, S. P. Colowick and N. C. Kaplan, 2, 987 (Academic Press, New York, 1955).
Slater, E. C., Biochem. J., 5, 521 (1953).
Mandel, P., and Klethi, J., C.R. Acad. Sci., Paris, 241, 710 (1955).
Kinoshita, J. H., Arch. Ophthal., 54, 360 (1955).
Martin, J. B., and Doty, D. M., Anal. Chem., 21, 965 (1949).
Ely, L. O., Arch. Ophthal., 47, 717 (1952).
Morrison, M., Ann. Rev. Biochem., 30, 11 (1961).
Slater, E. C., and Cleland, K. W., Biochem. J., 53, 557 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
VIRMAUX, N., MANDEL, P. Succinic Dehydrogenase Activity and Oxidative Phosphorylation of the Mitochondria in the Crystalline Lens of Bovines. Nature 197, 792–793 (1963). https://doi.org/10.1038/197792a0
Issue Date:
DOI: https://doi.org/10.1038/197792a0
This article is cited by
-
Les nucleosides polyphosphates du cristallin
Documenta Ophthalmologica (1970)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
