Abstract
IN previous communications1–3 the existence of precorticotrophin—a precursor of corticotrophin—was demonstrated in the anterior pituitary tissue of the ox. Later, I4 reported the presence of a material behaving like precorticotrophin in normal rabbit blood serum. Young5 observed that the insulin-like activity of the serum or plasma from arterial blood, or from blood oxygenated in vitro, was higher than that of serum or plasma from comparable venous blood, or blood deoxygenated in vitro. In view of this, it appeared worth while to investigate the presence of precorticotrophin-like material in sera obtained individually from arterial and venous blood.
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Dasgupta, P. R., and Young, F. G., Nature, 182, 32 (1958).
Dixon, H. B. F., Goth, A., and Young, F. G., Acta Physiol. Acad. Sci. Hung., 15, 133 (1959).
Dasgupta, P. R., Bull. Nat. Inst. Sci. India, No. 17, 117 (1962).
Dasgupta, P. R., Nature, 191, 1106 (1961).
Young, F. G., Mem. Soc. Endocrinol, edit. by Williams, P. C., 11, 101 (London).
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DASGUPTA, P. Distribution of Precorticotrophin in Blood. Nature 197, 388 (1963). https://doi.org/10.1038/197388a0
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DOI: https://doi.org/10.1038/197388a0
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