Abstract
THE effect of intravenous papain on the cartilage matrix has been reported by L. Thomas1. Recently we have been investigating the acute lipæmia induced by the injection of papain solution in adult rabbits2. At the end of each experiment, the animals were killed by air embolism and autopsies were performed. Several of these experimental animals showed lesions in the ascending aorta and the arch, and to a lesser extent in the upper portion of the descending aorta. This communication deals with the description of these lesions and of the conditions under which they were developed.
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References
Thomas, L., J. Exp. Med., 104, 245 (1956).
Tsaltas, T., Fed. Proc., 17, No. 1 (March 1958).
Tsaltas, T., J. Exp. Med., 108, 507 (1958).
Spicer, S. S., et al., Amer. J. Path., 104, 245 (1956).
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TSALTAS, T. Metaplasia of Aortic Connective Tissue to Cartilage and Bone induced by the Intravenous Injection of Papain. Nature 196, 1006–1007 (1962). https://doi.org/10.1038/1961006b0
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DOI: https://doi.org/10.1038/1961006b0
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