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Differential Autoradiography of Tritium and Another β-Emitter by a Double Stripping Film Technique

Abstract

CERTAIN investigations on cellular biochemistry may require examination of the simultaneous incorporation of two metabolites, or of the incorporation of the same metabolite at different times, by the same group of cells. These investigations may be carried out by administering metabolites labelled with two different isotopes—tritium and any other β-emitter—and then distinguishing their distributions on the same autoradiograph, by processing the respective photographic ‘grains’ to different colours.

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  1. Chapman-Andresen, C., C. R. Lab. Carlsberg., Ser. Chim., 28, 529 (1953).

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DAWSON, K., FIELD, E. & STEVENS, G. Differential Autoradiography of Tritium and Another β-Emitter by a Double Stripping Film Technique. Nature 195, 510–511 (1962). https://doi.org/10.1038/195510a0

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  • DOI: https://doi.org/10.1038/195510a0

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