Abstract
SINCE the discovery by Nirenberg and Matthaei1 that a synthetic polynucleotide, when added to an E. coli cell-free system, led to the synthesis of a specific polypeptide, various groups have used similar methods to find code letters, for the common amino-acids. We should like to report certain observations, some of which are at variance with those already published.
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References
Nirenberg, M. W., and Matthaei, J. H., Proc. U.S. Nat. Acad. Sci., 47, 1588 (1961).
Crick, F. H. C., Barnett, L., Brenner, S., and Watts-Tobin, R. J., Nature, 192, 1227 (1961).
Lengyel, P., Speyer, J. F., and Ochoa, S., Proc. U.S. Nat. Acad. Sci., 47, 1936 (1961). Lengyel, P., Speyer, J. F., Basilio, C., and Ochoa, S., ibid., 48, 282 (1962).
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BRETSCHER, M., GRUNBERG-MANAGO, M. Polyribonucleotide-directed Protein Synthesis using an E. coli Cell-free System. Nature 195, 283–284 (1962). https://doi.org/10.1038/195283a0
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DOI: https://doi.org/10.1038/195283a0
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