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Influence of Uterine Position on the Response of the Mouse Embryo to Anoxia

Abstract

THE exposure of the pregnant female mouse to the effects of a severe degree of anoxia results in the reduction of litter size and the birth of deformed young1. The object of the present investigation was to determine whether the chances of an embryo surviving the effects of anoxia were in any way affected by the position which it occupied in the uterine horn relative to its siblings.

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References

  1. Ingalls, T. H., Curley, F. J., and Prindle, R. A., New Eng. J. Med., 247, 758 (1952).

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  2. McLaren, A., and Michie, D., Ciba Found. Symp. Congenital Malformations, 178 (J. and A. Churchill, Ltd., London, 1960).

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  3. Woollam, D. H. M., and Millen, J. W., Nature, 190, 184 (1961).

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WOOLLAM, D., MILLEN, J. Influence of Uterine Position on the Response of the Mouse Embryo to Anoxia. Nature 194, 990–991 (1962). https://doi.org/10.1038/194990a0

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