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Isolation and Characterization of a Compound from the Urine of Schizophrenics

Abstract

THE systematic screening of schizophrenic and normal urine in this laboratory has led to the identification of a biologically active compound in urine of schizophrenics. This compound is of particular interest since it does not have the usual sympathomimetic actions of the closely related catecholamines, but does have a depressant effect on the central nervous system1.

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References

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FRIEDHOFF, A., WINKLE, E. Isolation and Characterization of a Compound from the Urine of Schizophrenics. Nature 194, 897–898 (1962). https://doi.org/10.1038/194897b0

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