Abstract
RECENTLY, Gray and Fowden1 have reported the isolation of a new amino-acid, 4-methylene proline (I), from seeds of loquat (Eriobotrya japonica). Structure (I) was firmly established by both chemical and spectroscopic evidence; but during the course of another investigation we have confirmed it by synthesis. This synthesis serves also to clarify some ambiguity concerning the optical configuration of the new amino-acid.
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BETHELL, M., KENNER, G. & SHEPPERD, R. 4-Methyleneproline : Synthetic Studies. Nature 194, 864 (1962). https://doi.org/10.1038/194864a0
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DOI: https://doi.org/10.1038/194864a0
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