Abstract
IN 19601, I pointed out that some simple modifications in the intravital dithizone (diphenyl-thiocarbazone) method used by histochemists2,3 for the display of zinc show clearly that the site of the specific (pink) staining in the neighbourhood of the hippocampal ‘CA3’ and ‘CA2’ pyramidal cells is topologically identical with the zone occupied by the ‘mossy fibre system’ (the axons of the granule cells of thefascia dentata); while the conspicuous arc of pink staining within the facia dentata is coincident with the ‘CA4’ cell-and-fibre zone. I interpreted these concentrations of zinc as histochemical peculiarities of the histoanatomically peculiar ‘syncytial periaxoplasm’ which the mossy fibre system exhibits, for most of its course, in ammoniacal-silver preparations1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
McLardy, T., Confin. Neurol., 20, 1 (1960).
Maske, H., Naturwiss., 42, 424 (1955).
Fleischhauer, K., and Horstmann, E., Z. Zellforsch., 46, 598 (1957).
Timm, F., Z. Zellforsch., 48, 548 (1958).
Hamlyn, L. H., Nature, 190, 645 (1961).
Paper read before The EEG Society on January 6, 1962.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McLARDY, T. Zinc Enzymes and the Hippocampal Mossy Fibre System. Nature 194, 300–302 (1962). https://doi.org/10.1038/194300a0
Issue Date:
DOI: https://doi.org/10.1038/194300a0
This article is cited by
-
Histochemical localization of zinc in the feline tapetum
Histochemistry (1981)
-
Distribution of heavy metals in the hippocampal region of the guinea pig
Zeitschrift f�r Zellforschung und mikroskopische Anatomie (1974)
-
Distribution of acetyl cholinesterase in the hippocampal region of the guinea pig
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1972)
-
Distribution of acetyl cholinesterase in the hippocampal region of the guinea pig
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1972)
-
Depletion of metal in the rat hippocampal mossy fibre system by intravital chelation with dithizone
Histochemie (1971)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
